Thus, after infection of hDFSCs or Ca9-22 with P. intermedia or T. forsythia accumulation of interleukins IL-6, IL-8 and IL-10 in the supernatant was quantified after 2 h, 4 h and 24 h of anaerobic co-culture (MOI = 100). The gene discussed is CXCL8; the disease is infection.