ERCC2 and cancer: For example, Mirecka et al. investigated 15 SNPs in seven XP genes (XPA-XPG) in a case-control study of 720 PCa patients and 1,121 cancer-free controls, and they found an increased risk of PCa was associated with the XPD SNP, rs1799793 (Asp312Asn) AG and AA genotypes [25].