In contrast, GM+R848+LPS conditioned, Ag-pulsed PBMC T-cell cultures exposed to IL-7 in addition to IL-2 displayed 80% or greater viability at d16, with a sustained proliferating compartment after d9 that demonstrated up to 80% Ag-specificity in ICC assays (Figure 2A, 2B and 8A-D). Here, IL2 is linked to intrahepatic cholangiocarcinoma.