SOAT1 and colonic neoplasm: We have shown that the crude extract from the plant American Ginseng (AG), and a product of its further fractionation – a Hexane fraction of AG (HAG)– effectively suppresses colitis and colon cancer through apoptosis of inflammatory cells and cell cycle arrest of colon cancer cells, involving preferential suppression of STAT/iNOS signaling in activated macrophages [13], prevention of DNA damage in colon cells [14], and prevention of colon cancer cell migration through enhanced miR-29b expression [15].