The two strongest sites of TRIM33 enrichment in B-ALL were located 117bp upstream of Bcl2l11/Bim gene (in an intron of Acoxl gene), and at a site 35 kb upstream of Atp1b3. We also found TRIM33 recruitment to these sequences in 32D and RAW cell lines, with additional TRIM33 peaks at the Bcl2l11/Bim locus in myeloid compared to lymphoid cells (Supplementary Figure S4A). The gene discussed is TRIM33; the disease is precursor B-cell acute lymphoblastic leukemia.