CLDN1 and metastatic malignant neoplasm in the lymph nodes: According to an analysis of the CLDN1 immunostaining scores of cervical cancer tissue with or without lymph node metastasis (Supplementary Table 1), we found that the strong positive staining for CLDN1 in the cervical lymph node metastasis group was significantly higher than the group with no lymph node metastasis of cervical cancer tissues (p < 0.05) (Figure 2C).