LDLR and coronary artery disorder: The T allele of the LDLR SNP rs6511720 (G>T) [MAF = 0.10 in a European population, (1000 Genomes Project Phase 3)] has been identified as being associated with lower plasma levels of LDL-C (size effect: -0.15 to -0.26 mmol/L) and a lower risk of CAD [19–21], myocardial infarction (MI) [22] and abdominal aortic aneurysm (AAA) [23].