KAT2B and cancer: Known to associate with CBP6 and p3006b during transcription, misregulation of PCAF has been linked to cancer,7 HIV infection,7a, 8 and neuroinflammation.7a, 9 Despite predictions of high druggability10 and links with inflammatory disease,7a, 11 the role of PCAF and, more specifically, contributions of the Brd in such disease states are poorly understood.