PBMCs from HCC patients had significantly higher percentages of PD-L1+MDSCs compared to those from healthy subjects (mean 0.41% vs 0.079%; p < 0.001) and patients with chronic hepatitis (mean 0.41% vs 0.20%; p < 0.05) (Fig. 1b). The gene discussed is CD274; the disease is hepatocellular carcinoma.