Compared to non-invasive MCF7, VE-cadherin overexpression was observed in metastatic breast cancer cells (SKBR3, MDA-MB-231 and MDA-MB-468) and metastatic melanoma cell lines (BLM, A375, SK-MEL-28 and Mel57) except SK-MEL-103. Here, CDH5 is linked to breast cancer.