The rise in PAI-1 correlated slightly with a parallel increase in TF (Figure 3A) and ROC curve analysis (Figure 4) revealed a sensitivity of 64% with AUC of 0.775; p = 0.024, which indicates a somewhat poorer test in favor of diagnosing ARDS, as compared with the corresponding test of TF. The gene discussed is SERPINE1; the disease is acute respiratory distress syndrome.