INRG includes the following: the stage of the disease according to the INRG Staging System, age at the time of diagnosis, histologic category, such as maturing ganglioneuroma versus ganglioneuroblastoma, intermixed versus ganglioneuroblastoma, or nodular versus neuroblastoma, grade or how cells of the tumor are differentiated, MYCN gene status, chromosome 11q status, and tumor cell ploidy, which is the DNA content of tumor cells. This evidence concerns the gene MYCN and ganglioneuroblastoma.