FOXP3 and atopic asthma: Interestingly, a recent study showed that patients with atopic asthma had a trend-wise higher average level of histone H3 acetylation in the FOXP3 promoter region compared with healthy controls, although this difference was not statistically significant (p = 0.07, n = 26, for the mean difference in H3 acetylation between atopic asthma cases and controls) [86].