The most frequently described proangiogenic tumor “switch on” factors include vascular endothelial growth factors (VEGFs), fibroblast growth factor (FGF), platelet-derived growth factor (PDGF), transforming growth factors (TGFs), epidermal growth factor (EGF), angiopoietins (Angs), and others [6, 26]. The gene discussed is EGF; the disease is neoplasm.