Percentage of lysis in anti-TEM7 targeted MDA-MB-231 cancer cells was higher than in SKOV3 cells (control assay) incubated with trastuzumab (74.8 ± 1.0% in MDA-MB-231 versus 61.8 ± 7.2% in SKOV3). The gene discussed is PLXDC1; the disease is cancer.