Inflammatory mediator mRNAs in OFC differed significantly between low-inflammatory controls and low- and high-inflammatory schizophrenia (except IL-8; (SERPINA3 F(2,68)=41.036, P<0.001; IL-1β F(2,68)=45.972, P<0.001; IL-6F(2,67)=8.319, P=0.001; IL-8F(2,68)=2.976, P=0.058); Figure 4 and Supplementary Figure 3). Here, IL1B is linked to schizophrenia.