The systemic nature of the thiamine deficiency was further indicated by the positive relationships between brain SumT and liver SumT (Fig. S4h), between somatic growth (SG) and liver SumT (Fig. 4g), between SG and liver/brain SumT ratio (Fig. S4i), and between brain TK activity and body condition index (BCI) (Fig. 4h). The gene discussed is TKT; the disease is Thiamine deficiency.