TKT and Thiamine deficiency: The systemic nature of the thiamine deficiency was indicated by the negative relationships between liver TK latency and white muscle SumT (Fig. 5d) and egg SumT and liver TK latency (Fig. 5e), as well as the positive relationships between egg SumT and liver TK activity (Fig. S5j), white muscle SumT and total weight (Fig. S5k), liver SumT and heart SumT (Fig. S5l), liver SumT and brain SumT (Fig. S5m), and heart SumT and liver/brain SumT ratio (P = 0.0076, R2 = 0.31, n = 22, not shown).