We identified only two lncRNAs in U251 cells, lnc-ITGA11-1 and lnc-DIRC1-1, for which the levels were not affected by meningitic E. coli infection, while the remaining ones exhibited similar decreases in hBMECs, U251 cells and HUVECs (Fig. 7B and D). The gene discussed is ITGA11; the disease is escherichia coli infection.