Whereas no significant difference was found according to mutational status in ET, CALR+ MF patients showed a trend towards lower nucleosome levels than JAK2V617F+, 0.22 (0.07–0.71) μg/mL vs. 0.46 (0.08–1.58) μg/mL, P = 0.06 (Mann-Whitney test), probably because they tended to cluster in a lower DIPSS Plus category. This evidence concerns the gene CALR and essential thrombocythemia.