Some studies showed DUSP4 could promote the progress of colorectal cancer 29, 30, 31 and breast malignancy 32, while some researches showed DUSP4 could inhibit the tumour development in colorectal cancer 33, breast cancer 17, 34, diffuse large B‐cell lymphoma 35, laryngeal cancer 36, head and neck squamous cell carcinoma 37. This evidence concerns the gene DUSP4 and laryngeal carcinoma.