This, coupled with the emerging idea that adult neurogenesis may contribute to psychiatric disorders, including schizophrenia (Kang et al., 2015), leads us to speculate that a disruption in CaV1.2 function or expression may play a significant role not only in cognition, but also in neuropsychiatric disorders by altering adult neurogenesis and degrading dentate gyrus function. Here, CACNA1C is linked to psychiatric disorder.