ICAM1 and chronic obstructive pulmonary disease: These findings suggest that NF‐κB activation might contribute to enhanced RV14 replication by increasing ICAM‐1 expression in the present study, as previously reported by Schneider et al., who demonstrated that increased RV replication was related to increased ICAM‐1 expression in tracheobronchial epithelial cells that were isolated from COPD patients 48.