A recent trial studied the effectiveness of QAX576, anti-IL-13 antibody, in 23 adult patients, demonstrating a significantly decrease of intraepithelial esophageal eosinophilia and of the expression of EoE-relevant esophageal transcripts, such as eotaxin-3, inducing a sustained clinical improvement [12, 54]. The gene discussed is IL13; the disease is eosinophilic esophagitis.