PPARα, PPARγ, RXRA and PGC-1α were increased by 69.66% (P < 0.05), 640.89% (P < 0.001), 140.08% (P < 0.001) and 289.80% (P < 0.001) in DS group compared with those in model group, respectively (Fig. 3). Here, PPARGC1A is linked to Dravet syndrome.