APOB and coronary artery disorder: Naturally there is a strong link to the metabolic process that is manifested in the connection to the metabolic biomarkers, specifically insulin resistance and glycated haemoglobin level.33,34 This connection may be largely mediated by the increased expenditure of energy, which produces favourable effects on CHD pathogenesis.10, 23 Moderate exercise is also related to changes in lipid factors such as increases in HDL cholesterol and decreases in LDL cholesterol and Apo B levels.33,34