A GWAS in German subjects identified rs6038071 (r2=0.001 with rs434410 in African ancestry populations from 1000 Genomes), 40 kb upstream of CSNK2A1, to be associated with familial colorectal cancer.40BRAF is usually amplified in somatic DNA from basal-like breast cancers,41 but to our knowledge, germline variation in BRAF has not been associated with breast cancer. Here, CSNK2A1 is linked to colorectal cancer.