IGHE and asthma: Preliminary findings from our group suggest that children with asthma who had high levels of urinary LTE4 or 11β-PGF2α (above the 75th percentile), as compared to those with low levels (below the 25th percentile), had a lower FEV1, increased bronchial responsiveness, increased IgE, and increased blood eosinophils, factors which may well reflect a more type 2-driven airway inflammation [94].