G6PD and Jaundice: In some patients, the presence of the most severely affected variants (Class I) as G6PD Zacatecas [37], Hamburg [39], Quilmes [52], Veracruz [37], Merlo [52], Yucatan [37], Tennessee [42], unnamed A1088T [55], and unnamed C1187G [54] mutants presented acute hemolytic anemia and jaundice.