In Ni’s study, exploiting the db/db transgenic type 2 diabetes mellitus (T2DM) and streptozocin (STZ)-induced type 1 diabetes mellitus (T1DM) models, they tried to inhibit ERK1/2 and DCM development with mito-TEMPO which is a physicochemical compound, one of the superoxide dismutase (SOD) mimetics targeting mitochondrial ROS. Here, SOD1 is linked to type 1 diabetes mellitus.