NFKB1 and diffuse large B-cell lymphoma: To evaluate the effects of pharmacological inhibition of NF-κB activation on transcription activities of NF-κB subunits and DLBCL cell growth and survival, we selected the proteasome inhibitor bortezomib (BZ), and the small molecule NF-κB inhibitor BAY 11-7082 (BAY-11) that selectively inhibits the phosphorylation and degradation of IκBɑ[45-47] in MS (GCB-DLBCL) cells.