RELA and diffuse large B-cell lymphoma: Multivariate survival analysis (Cox regression) for high p65 nuclear expression with adjustments for clinical variables confirmed that p65high was an independent adverse prognostic factor in patients with GCB-DLBCL and in patients with WT-TP53 DLBCL, but not in the overall study group, the ABC-DLBCL subgroup, or the MUT-TP53 DLBCL subgroup (Table 2).