Cases of DLBCL with wild-type TP53 (WT-TP53) had significantly lower levels of RELA mRNA (P = 0.018, Fig. 1D) and a trend toward lower nuclear p65 levels (P = 0.11) than those with mutated TP53 (MUT-TP53), suggesting that wild-type p53 suppressed RELA NF-κB expression. The gene discussed is TP53; the disease is diffuse large B-cell lymphoma.