We found high p65 nuclear expression was significantly associated with p50+ and p50high nuclear expression in overall DLBCL, GCB-DLBCL, and ABC-DLBCL (Table 1), suggesting the predominance of p65/p50 dimer activation via the canonical NF-κB pathway [9]. The gene discussed is NFKB1; the disease is diffuse large B-cell lymphoma.