Compared with non-carriers, the odds ratio for CHD was 0.99 (0.95–1.03) in 279Phe heterozygotes, and 0.93 (0.82–1.05) in 279Phe homozygotes (i.e. nearly complete loss of Lp-PLA2 function: Figure 3). Here, PLA2G7 is linked to coronary artery disorder.