We have previously shown that ORFV-CBP potently blocks the recruitment of monocytes and dendritic cells in skin inflammation models that use CC chemokine gradients, so it was of interest to investigate whether or not the BPSV-CBP that binds the neutrophil-attractants CXCL1, CXCL2 and CCL3, had the capability to block the recruitment of neutrophils to the site of skin inflammation. The gene discussed is CXCL1; the disease is dermatitis.