TNNT2 and familial dilated cardiomyopathy: In our current study, we found that the transgenic overexpression of wildtype Tnnt2 transcript, superimposed on mutant R141W Tnnt2 transcript, in Tnnt2R141W/+/TGWT mice largely abrogated the DCM phenotype observed in Tnnt2R141W/+ mice.