Therefore, the goals of our study were: (i) to investigate the relationships between the SNP rs3957357C>T in GSTA1 and the risk of HCC occurrence among European individuals; (ii) to measure GSTA1 mRNA expression in HCCs and (iii) to interpret these findings in the light of patient outcome after HCC resection. This evidence concerns the gene GSTA1 and hepatocellular carcinoma.