Therefore, we evaluated the sympathetic vasoconstriction and α1-adrenoceptor-mediated contractile responses, as well as the mRNA expressions for tyrosine hydroxylase and α1-adrenoceptors (α1A-, α1B- and α1D subtypes) in the corpus cavernosum of Townes SCD mice. This evidence concerns the gene TH and Schnyder corneal dystrophy.