Moreover, many common tumor biomarkers (such as carbohydrate antigen (CA) 125, CA19-9, and carcinoembryonic antigen) have been reported to be predictive of prognosis in HCC accompanied by portal vein tumor thrombosis [25], but none of these markers was found to show a predictive role or to be related to the expression of PCDH20 among the HCC patients in our study. This evidence concerns the gene CEACAM5 and neoplasm.