Of them, 23 are significantly differentially expressed in the zebrafish brain tumours (adjusted P-value <0.05; Table S4), which confirmed the mesenchymal nature of our tumour model as YAP and TAZ signalling has been shown to be highly related to the mesenchymal subtype of GBM (Bhat et al., 2011; Orr et al., 2011). The gene discussed is WWTR1; the disease is glioblastoma.