Interestingly, among the 82 zebrafish orthologues of mesenchymal GBM markers found to be significantly upregulated in our model, five genes were related to YAP signalling: YAP1, WWTR1, TGFBR2, ITGB2 and IQGAP1 (Table S3). The gene discussed is ITGB2; the disease is glioblastoma.