IL22 and infection: ILC3‐derived IL‐22 is required for survival and immunity to C. rodentium infection in immunocompromised mice, whereas in the presence of adaptive immunity ILC3‐derived IL‐22 is required to prevent morbidity in the early phase of infection before the generation of a bacteria‐specific T‐cell response.27, 114, 115, 116, 117 As both subsets of ILC3 produce IL‐22 in the intestine the relative contribution of these two subsets to anti‐bacterial immunity has proven controversial.