Increased synthesis of vasculogenesis-related cytokines and integrins (IL8, IL10, bFGF, PDGF, MMP2, integrin αV, β1, β2, and β8)Increased proliferation of CD14(++)/CD16(+) angiogenic mononuclear cells and reduced apoptotic cellsEnhance neovascularization in ischemic limb and repair myocardium after infarction through cellular and humoral mechanisms (Animal model). The gene discussed is CXCL8; the disease is infarction.