Earlier analysis of Dab2 tumor predisposable phenotypes was done using heterozygous knockout mice, which were observed to have frequent uterine hyperproliferation and atypia, and increased ovarian epithelial growth and changes (Yang et al., 2006), though no increased tumor incidence was reported in the characterization of a Dab2 conditional knockout line (using Meox2-Cre; Morris et al., 2002b). The gene discussed is MEOX2; the disease is neoplasm.