The tumor suppressor functions of Dab2 have been attributed to its roles in suppressing Ras/MAPK signaling (He et al., 2001; Zhou and Hsieh, 2001), epithelial organization (Sheng et al., 2000b; Yang et al., 2002b, 2007), and cell adhesion/migration (Chetrit et al., 2009; Chao and Kunz, 2009; Chetrit et al., 2009; Teckchandani et al., 2009; Xie et al., 2015). This evidence concerns the gene DAB2 and neoplasm.