After adjustment for age, BMI, CHD risk factors (hypertension, diabetes, smoking), vascular lesions ≥3, frame length, bracket number and levels of platelet activity indicators (RPA, MAR, sCD40L, P-selectin, MMP-9, sVCAM-1, and sE-selectin), data from multivariate analysis showed that the risk of MACE in IM+PM patients is 2.664 times higher than that in EM patients. The gene discussed is CD40LG; the disease is diabetes mellitus.