To further evaluate the effect on anxiety of increased vasopressin levels in amygdala, vasopressin (1 ng), vasopressin ((1 ng) + the vasopressin V1a receptor antagonist Manning compound (10 ng)) or vehicle (NaCl 0.9%) was infused at each of two sites 15 min before the EPM test, via cannulas stereotaxically placed in the CeA (Figure 9A). The gene discussed is AVPR1A; the disease is Anxiety.