VPS35 and Parkinson disease: Assuming the prevalence of rare VPS mutations from M-PD studies (0.105%) as due to F-PD, the prevalence of all VPS35 variants in F-PD (both p.Asp620Asn and all rare variants) is 0.391% (0.286% of p.Asp620Asn in F-PD + 0.105 % or rare variants in M-PD).