Statins lower LDL levels by blocking 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR), the rate-limiting enzyme of cholesterol synthesis, and have anti-cancer properties (Mucci and Stampfer, 2014; Chae et al., 2014; Gronich and Rennert, 2013). This evidence concerns the gene HMGCR and cancer.