Infection with EBOV/VP35m resulted in an increase, as compared to wt EBOV, in proliferation of both CD4+ and CD8+ T cells in PBMCs from each donor, with or without peptides, although the effect was weak for CD4+ T-cells with peptides, and the overall effect did not reach statistical significance due to the high donor-to-donor variability. This evidence concerns the gene CD8A and infection.