S. hyicus also secreted lipase, which was reported in many bacterial species as a potential contributor to colonization and persistence on the skin and is produced during bacterial infection [42–44]; Thus, lipase has been suggested as an important bacterial virulence factor and might play important role in the pathogenesis of S. hyicus. Bacterial ABC transporters are essential in cell viability, virulence, and pathogenicity. Here, ABCG2 is linked to bacterial infectious disease.