Interestingly, it has been shown that anti-TNF-α treatments are able to exert their effects also increasing the proportion of Tregs, while inhibiting the differentiation of Th17 cells in Behçet patients with uveitis.[10,11] This observation is very interesting in the light of our results; indeed anti-TNF-α could be effective in the early phases of gut involvement of Behçet patients due to both their direct capacity to inhibit the local production of TNF-α, as well as for their ability of modulate the T cells balance. Here, TNF is linked to uveitis.