Analysis of the hits using GOstat17 revealed that ribosomal proteins were enriched in this population in RPE1 cells (enriched GO terms: ribosome biogenesis (GO:0042254) p-value = 1.86e-19, rRNA processing (GO:0006364) p-value = 2.9e-16, cytosolic ribosome (GO:0005830) p-value = 1.51e-10), whereas many ribosomal proteins and proteins involved in ribosome biogenesis (e.g., WDR75) caused an increase in S-phase of the U2OS tumor cells (Fig. S1B). Here, WDR75 is linked to neoplasm.