Autophagy inhibition does not affect migration or invasiveness capacity of HCC cells but reduces cell death resistance and lung tissue colonization.27 Also, N-myc downstream regulated 1 (NDRG1), known for its role of metastasis suppressor, has been shown to inhibit stress-induced autophagic responses, suggesting that its anti-metastatic activity could rely on its ability to prevent pro-survival autophagy activation in cancer cells.28 This evidence concerns the gene NDRG1 and cancer.