Glutamine metabolism regulated by cancer-specific glutaminase (EC 3.5.1.2, glutaminase 1 (GLS1), L-glutaminase and glutamine aminohydrolase) has been gaining attention in cancer biology as it has been reported that high levels of kidney-type glutaminase (glutaminase 1, GLS1, KGA) are associated with oncogenic activation. Here, GLS2 is linked to cancer.