HER2 was clearly overexpressed (3+) at IHC with membranous staining in 26 cases: 18 FTC, of which 6 were widely invasive (see example in Figure 1A), and 8 PTC (2 classic, 5 follicular variant, and 1 Hürthle cell variant) (see example in Figure 1B). This evidence concerns the gene ERBB2 and thyroid cancer, nonmedullary, 2.